R5G (p.Arg5Gly) variant of REN (Renin)
R5G (p.Arg5Gly) in REN (Renin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
R5G (p.Arg5Gly) variant details
- p.Arg5Gly
- ExAC rs775844948
- gnomAD rs775844948
- Missense
- Variant Prioritization Score for Impact Estimate 0.303
- REVEL 0.05
- MetaLR 0.08
- MetaSVM -1.03
- CADD 15.40
- PolyPhen-2 0.00
- SIFT 0.26
- Most common in the South Asian population (allele frequency 3.5e-05)
- Structural context available