R55T (p.Arg55Thr) variant of REN (Renin)
R55T (p.Arg55Thr) in REN (Renin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
R55T (p.Arg55Thr) variant details
- p.Arg55Thr
- TOPMed rs756019722
- gnomAD rs756019722
- Missense
- Variant Prioritization Score for Impact Estimate 0.179
- REVEL 0.06
- MetaLR 0.07
- MetaSVM -1.03
- CADD 17.70
- PolyPhen-2 0.35
- SIFT 0.13
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available