P113S (p.Pro113Ser) variant of REN (Renin)
P113S (p.Pro113Ser) in REN (Renin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.61 / 1. The record also includes population frequency data and structural context.
P113S (p.Pro113Ser) variant details
- p.Pro113Ser
- gnomAD rs1474773230
- Missense
- Variant Prioritization Score for Impact Estimate 0.613
- REVEL 0.58
- MetaLR 0.37
- MetaSVM -0.25
- CADD 25.70
- PolyPhen-2 0.98
- SIFT 0.03
- Most common in the East Asian population (allele frequency 0.00019)
- Structural context available