N71D (p.Asn71Asp) variant of REN (Renin)
N71D (p.Asn71Asp) in REN (Renin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
N71D (p.Asn71Asp) variant details
- p.Asn71Asp
- ExAC rs767727275
- TOPMed rs767727275
- gnomAD rs767727275
- Missense
- Variant Prioritization Score for Impact Estimate 0.226
- REVEL 0.15
- MetaLR 0.09
- MetaSVM -1.08
- CADD 19.40
- PolyPhen-2 0.00
- SIFT 0.12
- Most common in the Middle Eastern population (allele frequency 0.001)
- Structural context available