M82K (p.Met82Lys) variant of REN (Renin)
M82K (p.Met82Lys) in REN (Renin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
M82K (p.Met82Lys) variant details
- p.Met82Lys
- ESP rs144219651
- ExAC rs144219651
- TOPMed rs144219651
- gnomAD rs144219651
- Missense
- Variant Prioritization Score for Impact Estimate 0.277
- REVEL 0.20
- MetaLR 0.13
- MetaSVM -0.91
- CADD 23.20
- PolyPhen-2 0.00
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 7.2e-05)
- Structural context available