M7L (p.Met7Leu) variant of REN (Renin)
M7L (p.Met7Leu) in REN (Renin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
M7L (p.Met7Leu) variant details
- p.Met7Leu
- ExAC rs746180535
- TOPMed rs746180535
- gnomAD rs746180535
- Missense
- Variant Prioritization Score for Impact Estimate 0.207
- REVEL 0.22
- MetaLR 0.09
- MetaSVM -1.03
- CADD 13.40
- PolyPhen-2 0.00
- SIFT 0.09
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available