M64V (p.Met64Val) variant of REN (Renin)
M64V (p.Met64Val) in REN (Renin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data and structural context.
M64V (p.Met64Val) variant details
- p.Met64Val
- TOPMed rs1045353423
- gnomAD rs1045353423
- Missense
- Variant Prioritization Score for Impact Estimate 0.0659
- REVEL 0.02
- MetaLR 0.05
- MetaSVM -1.04
- CADD 0.00
- PolyPhen-2 0.00
- SIFT 0.49
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available