M64L (p.Met64Leu) variant of REN (Renin)
M64L (p.Met64Leu) in REN (Renin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data and structural context.
M64L (p.Met64Leu) variant details
- p.Met64Leu
- TOPMed rs1045353423
- gnomAD rs1045353423
- Missense
- Variant Prioritization Score for Impact Estimate 0.0768
- REVEL 0.04
- MetaLR 0.05
- MetaSVM -1.04
- CADD 0.01
- SIFT 0.67
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available