M53T (p.Met53Thr) variant of REN (Renin)
M53T (p.Met53Thr) in REN (Renin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
M53T (p.Met53Thr) variant details
- p.Met53Thr
- gnomAD rs1194228285
- Missense
- Variant Prioritization Score for Impact Estimate 0.173
- REVEL 0.05
- MetaLR 0.07
- MetaSVM -1.06
- CADD 22.70
- PolyPhen-2 0.02
- SIFT 0.06
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available