M180T (p.Met180Thr) variant of REN (Renin)
M180T (p.Met180Thr) in REN (Renin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
M180T (p.Met180Thr) variant details
- p.Met180Thr
- ExAC rs775027150
- gnomAD rs775027150
- Missense
- Variant Prioritization Score for Impact Estimate 0.311
- REVEL 0.14
- MetaLR 0.09
- MetaSVM -0.96
- CADD 21.60
- PolyPhen-2 0.28
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available