M173I (p.Met173Ile) variant of REN (Renin)
M173I (p.Met173Ile) in REN (Renin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
M173I (p.Met173Ile) variant details
- p.Met173Ile
- TOPMed rs1658207388
- Missense
- Variant Prioritization Score for Impact Estimate 0.122
- REVEL 0.14
- MetaLR 0.03
- MetaSVM -1.05
- CADD 0.00
- PolyPhen-2 0.00
- SIFT 0.11
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available