L15P (p.Leu15Pro) variant of REN (Renin)
L15P (p.Leu15Pro) in REN (Renin) is a missense change. Clinical records from ClinVar and UniProt describe it as uncertain significance in the context of Familial juvenile hyperuricemic nephropathy type 2. The record also includes variant effect predictions and structural context.
L15P (p.Leu15Pro) variant details
- p.Leu15Pro
- NCI-TCGA Cosmic COSV9968
- Uncertain significance
- Familial juvenile hyperuricemic nephropathy type 2
- Missense
- SIFT 0.12
- ClinVar: Uncertain significance (Familial juvenile hyperuricemic nephropathy type 2)
- UniProt: Uncertain significance
- Structural context available