L147I (p.Leu147Ile) variant of REN (Renin)
L147I (p.Leu147Ile) in REN (Renin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
L147I (p.Leu147Ile) variant details
- p.Leu147Ile
- gnomAD rs1658227171
- Missense
- Variant Prioritization Score for Impact Estimate 0.237
- REVEL 0.12
- MetaLR 0.02
- MetaSVM -0.99
- CADD 10.40
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available