I77M (p.Ile77Met) variant of REN (Renin)
I77M (p.Ile77Met) in REN (Renin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
I77M (p.Ile77Met) variant details
- p.Ile77Met
- ESP rs141467355
- TOPMed rs141467355
- gnomAD rs141467355
- Missense
- Variant Prioritization Score for Impact Estimate 0.164
- REVEL 0.03
- MetaLR 0.09
- MetaSVM -1.04
- CADD 16.60
- SIFT 0.16
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available