I162T (p.Ile162Thr) variant of REN (Renin)
I162T (p.Ile162Thr) in REN (Renin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
I162T (p.Ile162Thr) variant details
- p.Ile162Thr
- ExAC rs749571526
- gnomAD rs749571526
- Missense
- Variant Prioritization Score for Impact Estimate 0.124
- REVEL 0.12
- MetaLR 0.04
- MetaSVM -1.01
- CADD 2.37
- PolyPhen-2 0.00
- SIFT 0.92
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available