G93S (p.Gly93Ser) variant of REN (Renin)
G93S (p.Gly93Ser) in REN (Renin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.82 / 1. The record also includes population frequency data and structural context.
G93S (p.Gly93Ser) variant details
- p.Gly93Ser
- TOPMed rs1475981961
- gnomAD rs1475981961
- Missense
- Variant Prioritization Score for Impact Estimate 0.824
- REVEL 0.95
- MetaLR 0.94
- MetaSVM 1.09
- CADD 27.50
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 5e-05)
- Structural context available