G93D (p.Gly93Asp) variant of REN (Renin)
G93D (p.Gly93Asp) in REN (Renin) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.89 / 1. The record also includes population frequency data and structural context.
G93D (p.Gly93Asp) variant details
- p.Gly93Asp
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.89
- REVEL 0.96
- MetaLR 0.94
- MetaSVM 1.09
- CADD 26.80
- PolyPhen-2 1.00
- SIFT 0.00
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available