G70D (p.Gly70Asp) variant of REN (Renin)
G70D (p.Gly70Asp) in REN (Renin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
G70D (p.Gly70Asp) variant details
- p.Gly70Asp
- ExAC rs773505649
- TOPMed rs773505649
- gnomAD rs773505649
- Missense
- Variant Prioritization Score for Impact Estimate 0.161
- REVEL 0.04
- MetaLR 0.09
- MetaSVM -1.02
- CADD 2.55
- PolyPhen-2 0.00
- SIFT 0.09
- Most common in the HGDP:BURUSHO population (allele frequency 0.042)
- Structural context available