G57S (p.Gly57Ser) variant of REN (Renin)
G57S (p.Gly57Ser) in REN (Renin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data and structural context.
G57S (p.Gly57Ser) variant details
- p.Gly57Ser
- ExAC rs777584055
- TOPMed rs777584055
- gnomAD rs777584055
- Missense
- Variant Prioritization Score for Impact Estimate 0.0708
- REVEL 0.02
- MetaLR 0.05
- MetaSVM -1.04
- CADD 0.25
- PolyPhen-2 0.02
- SIFT 0.75
- Most common in the Finnish in Finland (FIN) population (allele frequency 9.4e-05)
- Structural context available