G167R (p.Gly167Arg) variant of REN (Renin)
G167R (p.Gly167Arg) in REN (Renin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data and structural context.
G167R (p.Gly167Arg) variant details
- p.Gly167Arg
- cosmic curated COSV10808
- TOPMed rs1326333821
- gnomAD rs1326333821
- Missense
- Variant Prioritization Score for Impact Estimate 0.57
- REVEL 0.61
- MetaLR 0.46
- MetaSVM -0.00
- CADD 27.60
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available