G167E (p.Gly167Glu) variant of REN (Renin)
G167E (p.Gly167Glu) in REN (Renin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.54 / 1. The record also includes population frequency data and structural context.
G167E (p.Gly167Glu) variant details
- p.Gly167Glu
- cosmic curated COSV65818
- Ensembl rs138459586
- Missense
- Variant Prioritization Score for Impact Estimate 0.538
- REVEL 0.44
- MetaLR 0.27
- MetaSVM -0.56
- CADD 24.90
- PolyPhen-2 0.88
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available