F31L (p.Phe31Leu) variant of REN (Renin)
F31L (p.Phe31Leu) in REN (Renin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
F31L (p.Phe31Leu) variant details
- p.Phe31Leu
- gnomAD rs1203318715
- Missense
- Variant Prioritization Score for Impact Estimate 0.218
- REVEL 0.09
- MetaLR 0.07
- MetaSVM -1.00
- CADD 15.50
- PolyPhen-2 0.03
- SIFT 1.00
- Most common in the East Asian population (allele frequency 0.00019)
- Structural context available