F103S (p.Phe103Ser) variant of REN (Renin)
F103S (p.Phe103Ser) in REN (Renin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.75 / 1. The record also includes population frequency data and structural context.
F103S (p.Phe103Ser) variant details
- p.Phe103Ser
- gnomAD rs1211712060
- Missense
- Variant Prioritization Score for Impact Estimate 0.746
- REVEL 0.90
- MetaLR 0.59
- MetaSVM 0.50
- CADD 29.80
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available