D52H (p.Asp52His) variant of REN (Renin)
D52H (p.Asp52His) in REN (Renin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
D52H (p.Asp52His) variant details
- p.Asp52His
- ExAC rs745849711
- gnomAD rs745849711
- Missense
- Variant Prioritization Score for Impact Estimate 0.198
- REVEL 0.03
- MetaLR 0.07
- MetaSVM -1.01
- CADD 21.80
- PolyPhen-2 0.11
- SIFT 0.11
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available