D131E (p.Asp131Glu) variant of REN (Renin)
D131E (p.Asp131Glu) in REN (Renin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
D131E (p.Asp131Glu) variant details
- p.Asp131Glu
- 1000Genomes rs144089286
- ESP rs144089286
- ExAC rs144089286
- TOPMed rs144089286
- Missense
- Variant Prioritization Score for Impact Estimate 0.317
- REVEL 0.15
- MetaLR 0.17
- MetaSVM -0.89
- CADD 18.40
- PolyPhen-2 0.01
- SIFT 0.01
- Most common in the Latino/Admixed American population (allele frequency 0.00013)
- Structural context available