R158Q (p.Arg158Gln) variant of RELA (Transcription factor p65)
R158Q (p.Arg158Gln) in RELA (Transcription factor p65) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.74 / 1. The record also includes population frequency data.
R158Q (p.Arg158Gln) variant details
- p.Arg158Gln
- ESP rs375925395
- ExAC rs375925395
- TOPMed rs375925395
- gnomAD rs375925395
- Missense
- Variant Prioritization Score for Impact Estimate 0.737
- REVEL 0.67
- CADD 32.00
- PolyPhen-2 0.94
- SIFT 0.03
- Most common in the East Asian population (allele frequency 2.5e-05)