P106Q (p.Pro106Gln) variant of RELA (Transcription factor p65)
P106Q (p.Pro106Gln) in RELA (Transcription factor p65) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data.
P106Q (p.Pro106Gln) variant details
- p.Pro106Gln
- ExAC rs774014347
- TOPMed rs774014347
- gnomAD rs774014347
- Missense
- Variant Prioritization Score for Impact Estimate 0.413
- REVEL 0.16
- CADD 24.30
- PolyPhen-2 0.46
- SIFT 0.29
- Most common in the African/African-American population (allele frequency 4.8e-05)