L104F (p.Leu104Phe) variant of RELA (Transcription factor p65)
L104F (p.Leu104Phe) in RELA (Transcription factor p65) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data and structural context.
L104F (p.Leu104Phe) variant details
- p.Leu104Phe
- ExAC rs773613820
- gnomAD rs773613820
- Missense
- Variant Prioritization Score for Impact Estimate 0.418
- REVEL 0.16
- CADD 24.10
- PolyPhen-2 1.00
- SIFT 0.54
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available