I8M (p.Ile8Met) variant of RELA (Transcription factor p65)
I8M (p.Ile8Met) in RELA (Transcription factor p65) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data.
I8M (p.Ile8Met) variant details
- p.Ile8Met
- gnomAD rs1169785805
- Missense
- Variant Prioritization Score for Impact Estimate 0.335
- REVEL 0.10
- CADD 25.00
- PolyPhen-2 0.45
- SIFT 0.13
- Most common in the South Asian population (allele frequency 1.2e-05)