T19S (p.Thr19Ser) variant of RBM10 (RNA-binding protein 10)
T19S (p.Thr19Ser) in RBM10 (RNA-binding protein 10) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data, experimental measurements, and structural context.
T19S (p.Thr19Ser) variant details
- p.Thr19Ser
- TOPMed rs1420226129
- gnomAD rs1420226129
- Missense
- Variant Prioritization Score for Impact Estimate 0.271
- REVEL 0.09
- CADD 16.10
- PolyPhen-2 0.02
- SIFT 0.81
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.00091)
- Structural context available
- RBM10 Zinc finger, RanBP2-type domain domainome 1.0: score -1.17