S22P (p.Ser22Pro) variant of RBM10 (RNA-binding protein 10)
S22P (p.Ser22Pro) in RBM10 (RNA-binding protein 10) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data, experimental measurements, and structural context.
S22P (p.Ser22Pro) variant details
- p.Ser22Pro
- Ensembl rs2147128005
- Missense
- Variant Prioritization Score for Impact Estimate 0.154
- REVEL 0.04
- CADD 21.90
- PolyPhen-2 0.10
- SIFT 0.15
- Most common in the 1KG:MSL population (allele frequency 0.013)
- Structural context available
- RBM10 Zinc finger, RanBP2-type domain domainome 1.0: score -0.56