R6P (p.Arg6Pro) variant of RBM10 (RNA-binding protein 10)
R6P (p.Arg6Pro) in RBM10 (RNA-binding protein 10) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data, experimental measurements, and structural context.
R6P (p.Arg6Pro) variant details
- p.Arg6Pro
- Ensembl rs2147065970
- Missense
- Variant Prioritization Score for Impact Estimate 0.394
- REVEL 0.12
- CADD 34.00
- PolyPhen-2 0.45
- SIFT 0.00
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.00019)
- Structural context available
- RBM10 Zinc finger, RanBP2-type domain domainome 1.0: score -0.347