G27S (p.Gly27Ser) variant of RBM10 (RNA-binding protein 10)
G27S (p.Gly27Ser) in RBM10 (RNA-binding protein 10) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.68 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
G27S (p.Gly27Ser) variant details
- p.Gly27Ser
- rs2147064658
- gnomAD X-47147395-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.684
- CADD 23.70
- Most common in the African/African-American population (allele frequency 0.00041)
- Structural context available
- RBM10 Zinc finger, RanBP2-type domain domainome 1.0: score -0.182
- Literature evidence available