p.Lys37dup variant of RASA1 (Ras GTPase-activating protein 1)

Name: RASA1 p.Lys37dup variant | CATVariant
Creator: Center for Precision Medicine and Data Sciences
Published: 2026-08-21
License: https://catvariant.com/terms-of-use

p.Lys37dup in RASA1 (Ras GTPase-activating protein 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.

p.Lys37dup variant details

rs1753671437
gnomAD 5-87268558-T-TGAA
Inframe Insertion
Variant Prioritization Score for Impact Estimate 0.263
CADD 17.10
Most common in the African/African-American population (allele frequency 2.4e-05)
Structural context available
RASA1 SH3 domain domainome 1.0: score 0.024
Literature evidence available