R35G (p.Arg35Gly) variant of RASA1 (Ras GTPase-activating protein 1)
R35G (p.Arg35Gly) in RASA1 (Ras GTPase-activating protein 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data, experimental measurements, and structural context.
R35G (p.Arg35Gly) variant details
- p.Arg35Gly
- TOPMed rs1161338399
- gnomAD rs1161338399
- Missense
- Variant Prioritization Score for Impact Estimate 0.505
- REVEL 0.46
- CADD 24.80
- PolyPhen-2 0.93
- SIFT 0.00
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.00028)
- Structural context available
- RASA1 SH3 domain domainome 1.0: score -0.268