K37T (p.Lys37Thr) variant of RASA1 (Ras GTPase-activating protein 1)
K37T (p.Lys37Thr) in RASA1 (Ras GTPase-activating protein 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
K37T (p.Lys37Thr) variant details
- p.Lys37Thr
- gnomAD 5-87268561-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.188
- REVEL 0.12
- CADD 20.40
- PolyPhen-2 0.01
- SIFT 0.02
- Most common in the South Asian population (allele frequency 5.9e-05)
- Structural context available
- RASA1 SH3 domain domainome 1.0: score 0.024
- Literature evidence available