G26S (p.Gly26Ser) variant of RASA1 (Ras GTPase-activating protein 1)
G26S (p.Gly26Ser) in RASA1 (Ras GTPase-activating protein 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
G26S (p.Gly26Ser) variant details
- p.Gly26Ser
- gnomAD 5-87268527-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.234
- REVEL 0.09
- CADD 20.20
- PolyPhen-2 0.00
- SIFT 0.50
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available
- RASA1 SH3 domain domainome 1.0: score -0.0284
- Literature evidence available