G22G (p.Gly22Gly) variant of RASA1 (Ras GTPase-activating protein 1)
G22G (p.Gly22Gly) in RASA1 (Ras GTPase-activating protein 1) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
G22G (p.Gly22Gly) variant details
- p.Gly22Gly
- rs1753666309
- gnomAD 5-87268517-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.244
- CADD 10.70
- Most common in the African/African-American population (allele frequency 6.1e-05)
- Structural context available
- RASA1 SH3 domain domainome 1.0: score -0.102
- Literature evidence available