A25S (p.Ala25Ser) variant of RASA1 (Ras GTPase-activating protein 1)
A25S (p.Ala25Ser) in RASA1 (Ras GTPase-activating protein 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
A25S (p.Ala25Ser) variant details
- p.Ala25Ser
- gnomAD 5-87268524-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.24
- REVEL 0.13
- CADD 17.30
- PolyPhen-2 0.01
- SIFT 0.05
- Population evidence available
- Structural context available
- RASA1 SH3 domain domainome 1.0: score -0.948
- Literature evidence available