Y24F (p.Tyr24Phe) variant of RARA (Retinoic acid receptor alpha)
Y24F (p.Tyr24Phe) in RARA (Retinoic acid receptor alpha) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.63 / 1. The record also includes population frequency data and structural context.
Y24F (p.Tyr24Phe) variant details
- p.Tyr24Phe
- TOPMed rs2033683761
- gnomAD rs2033683761
- Missense
- Variant Prioritization Score for Impact Estimate 0.634
- REVEL 0.64
- CADD 23.80
- PolyPhen-2 0.90
- SIFT 0.25
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available