M31V (p.Met31Val) variant of RARA (Retinoic acid receptor alpha)
M31V (p.Met31Val) in RARA (Retinoic acid receptor alpha) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
M31V (p.Met31Val) variant details
- p.Met31Val
- cosmic curated COSV99564
- TOPMed rs1313589879
- gnomAD rs1313589879
- Missense
- Variant Prioritization Score for Impact Estimate 0.33
- REVEL 0.28
- CADD 15.40
- PolyPhen-2 0.00
- SIFT 0.74
- Most common in the Middle Eastern population (allele frequency 0.00017)
- Structural context available