G14E (p.Gly14Glu) variant of RARA (Retinoic acid receptor alpha)
G14E (p.Gly14Glu) in RARA (Retinoic acid receptor alpha) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.69 / 1. The record also includes population frequency data and structural context.
G14E (p.Gly14Glu) variant details
- p.Gly14Glu
- Ensembl rs1567751373
- Missense
- Variant Prioritization Score for Impact Estimate 0.689
- REVEL 0.62
- CADD 25.50
- PolyPhen-2 0.99
- SIFT 0.01
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available