F26L (p.Phe26Leu) variant of RARA (Retinoic acid receptor alpha)
F26L (p.Phe26Leu) in RARA (Retinoic acid receptor alpha) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
F26L (p.Phe26Leu) variant details
- p.Phe26Leu
- ExAC rs746187167
- gnomAD rs746187167
- Missense
- Variant Prioritization Score for Impact Estimate 0.409
- REVEL 0.31
- CADD 20.30
- PolyPhen-2 0.01
- SIFT 0.16
- Most common in the South Asian population (allele frequency 2.3e-05)
- Structural context available