A25S (p.Ala25Ser) variant of RARA (Retinoic acid receptor alpha)
A25S (p.Ala25Ser) in RARA (Retinoic acid receptor alpha) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data and structural context.
A25S (p.Ala25Ser) variant details
- p.Ala25Ser
- 1000Genomes rs371882393
- ESP rs371882393
- ExAC rs371882393
- TOPMed rs371882393
- Missense
- Variant Prioritization Score for Impact Estimate 0.459
- REVEL 0.27
- CADD 21.80
- PolyPhen-2 0.01
- SIFT 0.14
- Most common in the 1KG:MSL population (allele frequency 0.0063)
- Structural context available