W59R (p.Trp59Arg) variant of RAMP1 (O60894)
W59R (p.Trp59Arg) in RAMP1 (O60894) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.62 / 1. The record also includes population frequency data, published literature, and structural context.
W59R (p.Trp59Arg) variant details
- p.Trp59Arg
- gnomAD 2-237877346-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.618
- REVEL 0.59
- CADD 27.90
- PolyPhen-2 0.99
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available