W56L (p.Trp56Leu) variant of RAMP1 (O60894)
W56L (p.Trp56Leu) in RAMP1 (O60894) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data and structural context.
W56L (p.Trp56Leu) variant details
- p.Trp56Leu
- ESP rs373719548
- ExAC rs373719548
- TOPMed rs373719548
- gnomAD rs373719548
- Missense
- Variant Prioritization Score for Impact Estimate 0.574
- REVEL 0.43
- CADD 25.80
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 5e-05)
- Structural context available