W56C (p.Trp56Cys) variant of RAMP1 (O60894)
W56C (p.Trp56Cys) in RAMP1 (O60894) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.66 / 1. The record also includes population frequency data and structural context.
W56C (p.Trp56Cys) variant details
- p.Trp56Cys
- ESP rs147407024
- ExAC rs147407024
- TOPMed rs147407024
- gnomAD rs147407024
- Missense
- Variant Prioritization Score for Impact Estimate 0.657
- REVEL 0.65
- CADD 26.20
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 6e-05)
- Structural context available