W14L (p.Trp14Leu) variant of RAMP1 (O60894)
W14L (p.Trp14Leu) in RAMP1 (O60894) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
W14L (p.Trp14Leu) variant details
- p.Trp14Leu
- TOPMed rs2062113418
- gnomAD rs2062113418
- Missense
- Variant Prioritization Score for Impact Estimate 0.351
- REVEL 0.13
- CADD 23.50
- PolyPhen-2 0.00
- SIFT 0.14
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available