T54S (p.Thr54Ser) variant of RAMP1 (O60894)
T54S (p.Thr54Ser) in RAMP1 (O60894) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data and structural context.
T54S (p.Thr54Ser) variant details
- p.Thr54Ser
- ExAC rs753345064
- TOPMed rs753345064
- gnomAD rs753345064
- Missense
- Variant Prioritization Score for Impact Estimate 0.0751
- REVEL 0.07
- CADD 0.32
- PolyPhen-2 0.25
- SIFT 0.77
- Most common in the Non-Finnish European population (allele frequency 5.4e-06)
- Structural context available