R3W (p.Arg3Trp) variant of RAMP1 (O60894)
R3W (p.Arg3Trp) in RAMP1 (O60894) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
R3W (p.Arg3Trp) variant details
- p.Arg3Trp
- Ensembl rs2062112846
- Missense
- Variant Prioritization Score for Impact Estimate 0.31
- REVEL 0.04
- CADD 23.10
- PolyPhen-2 0.45
- SIFT 0.03
- Most common in the African/African-American population (allele frequency 3.6e-05)
- Structural context available